Thursday, 3 March 2011

One dose short of an enzyme

Oncology Nurse Karen says the burning hands and feet are caused by excess chemo. Xeloda becomes effective when processed by the DPD enzyme (google for full title - my touch typing's not good enough on the iPad). People have different levels of DPD - if you have none, Xeloda can be lethal. Towards the end of my last cycle I must have been a bit short on DPD; hence spare chemo burning my extremities. If it gets bad they'll reduce the dose but 4 days into my 4th cycle and all's well.

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